Bioavailability given Effective and Administrative Dose Solution

STEP 0: Pre-Calculation Summary
Formula Used
Bioavailability = Effective Dose/Administered Dose
B = De/Da
This formula uses 3 Variables
Variables Used
Bioavailability - The Bioavailability is the systemically available fraction of a drug.
Effective Dose - (Measured in Kilogram) - The Effective Dose is a dose or concentration of a drug that produces a biological response.
Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
STEP 1: Convert Input(s) to Base Unit
Effective Dose: 5.5 Microgram --> 5.5E-09 Kilogram (Check conversion here)
Administered Dose: 3.5 Microgram --> 3.5E-09 Kilogram (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
B = De/Da --> 5.5E-09/3.5E-09
Evaluating ... ...
B = 1.57142857142857
STEP 3: Convert Result to Output's Unit
1.57142857142857 --> No Conversion Required
FINAL ANSWER
1.57142857142857 1.571429 <-- Bioavailability
(Calculation completed in 00.004 seconds)

Credits

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K J Somaiya College of science (K J Somaiya), Mumbai
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4 Bioavailability Calculators

Bioavailability of Drug
Go Bioavailability of Drug = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Dose Non-Intravenous)
Bioavailability given Rate of Administration and Dosing Interval
Go Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity)
Bioavailability given Drug Purity
Go Bioavailability = Effective Dose/(Drug Purity*Administered Dose)
Bioavailability given Effective and Administrative Dose
Go Bioavailability = Effective Dose/Administered Dose

Bioavailability given Effective and Administrative Dose Formula

Bioavailability = Effective Dose/Administered Dose
B = De/Da

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Bioavailability given Effective and Administrative Dose?

Bioavailability given Effective and Administrative Dose calculator uses Bioavailability = Effective Dose/Administered Dose to calculate the Bioavailability, The Bioavailability given effective and administrative dose formula is defined as the ratio of the effective dose and administered dose of the particular drug. Bioavailability is denoted by B symbol.

How to calculate Bioavailability given Effective and Administrative Dose using this online calculator? To use this online calculator for Bioavailability given Effective and Administrative Dose, enter Effective Dose (De) & Administered Dose (Da) and hit the calculate button. Here is how the Bioavailability given Effective and Administrative Dose calculation can be explained with given input values -> 1.571429 = 5.5E-09/3.5E-09.

FAQ

What is Bioavailability given Effective and Administrative Dose?
The Bioavailability given effective and administrative dose formula is defined as the ratio of the effective dose and administered dose of the particular drug and is represented as B = De/Da or Bioavailability = Effective Dose/Administered Dose. The Effective Dose is a dose or concentration of a drug that produces a biological response & Administered Dose is the amount of drug administered for a pharmacological response.
How to calculate Bioavailability given Effective and Administrative Dose?
The Bioavailability given effective and administrative dose formula is defined as the ratio of the effective dose and administered dose of the particular drug is calculated using Bioavailability = Effective Dose/Administered Dose. To calculate Bioavailability given Effective and Administrative Dose, you need Effective Dose (De) & Administered Dose (Da). With our tool, you need to enter the respective value for Effective Dose & Administered Dose and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Bioavailability?
In this formula, Bioavailability uses Effective Dose & Administered Dose. We can use 2 other way(s) to calculate the same, which is/are as follows -
  • Bioavailability = Effective Dose/(Drug Purity*Administered Dose)
  • Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity)
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