Dissociation Rate Constant from Michaelis Menten kinetics equation Solution

STEP 0: Pre-Calculation Summary
Formula Used
Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration)
KD = ((Vmax*S)/V0)-(S)
This formula uses 4 Variables
Variables Used
Dissociation Rate Constant - (Measured in Mole per Cubic Meter) - The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
Maximum Rate - (Measured in Mole per Cubic Meter Second) - The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
STEP 1: Convert Input(s) to Base Unit
Maximum Rate: 40 Mole per Liter Second --> 40000 Mole per Cubic Meter Second (Check conversion here)
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)
Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
KD = ((Vmax*S)/V0)-(S) --> ((40000*1500)/450)-(1500)
Evaluating ... ...
KD = 131833.333333333
STEP 3: Convert Result to Output's Unit
131833.333333333 Mole per Cubic Meter -->131.833333333333 Mole per Liter (Check conversion here)
FINAL ANSWER
131.833333333333 131.8333 Mole per Liter <-- Dissociation Rate Constant
(Calculation completed in 00.004 seconds)

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25 Michaelis Menten Kinetics Equation Calculators

Michaelis Constant given Modifying Factor in Michaelis Menten Equation
Go Michaelis Constant = (Substrate Concentration*((1/Enzyme Substrate Modifying Factor)*Maximum Rate)-Initial Reaction Rate)/((Enzyme Modifying Factor/Enzyme Substrate Modifying Factor)*Substrate Concentration)
Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation
Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration))
Modifying Factor of Enzyme Substrate Complex in Michaelis Menten Equation
Go Enzyme Substrate Modifying Factor = (((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Enzyme Modifying Factor*Michaelis Constant))/Substrate Concentration
Maximum Rate given Modifying Factor in Michaelis Menten Equation
Go Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration
Modifying Factor of Enzyme in Michaelis Menten Equation
Go Enzyme Modifying Factor = (((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Enzyme Substrate Modifying Factor*Substrate Concentration))/Michaelis Constant
Catalytic Rate Constant from Michaelis Menten Kinetics Equation
Go Catalytic Rate Constant for MM = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)
Enzyme Concentration from Michaelis Menten Kinetics equation
Go Initial Concentration of Enzyme = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Catalytic Rate Constant*Substrate Concentration)
Michaelis Constant given Catalytic Rate Constant and Initial Enzyme Concentration
Go Michaelis Constant = (Substrate Concentration*((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate))/Initial Reaction Rate
Michaelis Constant at Low Substrate Concentration
Go Michaelis Constant = (Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate
Dissociation Rate Constant from Michaelis Menten kinetics equation
Go Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration)
Initial Rate given Apparent value of Michaelis Menten Constant
Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Apparent Michaelis Constant+Substrate Concentration)
Maximum Rate given Apparent Value of Michaelis Menten Constant
Go Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration
Maximum Rate of System from Michaelis Menten Kinetics equation
Go Maximum Rate = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/Substrate Concentration
Substrate Concentration from Michaelis Menten Kinetics Equation
Go Substrate Concentration = (Michaelis Constant*Initial Reaction Rate)/(Maximum Rate-Initial Reaction Rate)
Michaelis Constant from Michaelis Menten kinetics equation
Go Michaelis Constant = Substrate Concentration*((Maximum Rate-Initial Reaction Rate)/Initial Reaction Rate)
Inhibitor's Dissociation Constant given Michaelis Menten Constant
Go Enzyme Inhibitor Dissociation Constant = (Inhibitor Concentration/((Apparent Michaelis Constant/Michaelis Constant)-1))
Michaelis Menten constant given Apparent Michaelis Menten Constant
Go Michaelis Constant = Apparent Michaelis Constant/(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))
Inhibitor Concentration given Apparent Michaelis Menten Constant
Go Inhibitor Concentration = ((Apparent Michaelis Constant/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant
Michaelis Constant given Forward, Reverse, and Catalytic Rate Constants
Go Michaelis Constant = (Reverse Rate Constant+Catalytic Rate Constant)/Forward Rate Constant
Catalytic rate constant given Michaelis Constant
Go Catalytic Rate Constant = (Michaelis Constant*Forward Rate Constant)-Reverse Rate Constant
Forward Rate Constant given Michaelis Constant
Go Forward Rate Constant = (Reverse Rate Constant+Catalytic Rate Constant)/Michaelis Constant
Michaelis Constant given Maximum Rate at Low Substrate Concentration
Go Michaelis Constant = (Maximum Rate*Substrate Concentration)/Initial Reaction Rate
Initial Enzyme Concentration if Substrate Concentration is Higher than Michaelis Constant
Go Enzyme Concentration Initially = Maximum Rate/Catalytic Rate Constant
Catalytic Rate Constant if Substrate Concentration is higher than Michaelis Constant
Go Catalytic Rate Constant = Maximum Rate/Initial Enzyme Concentration
Maximum Rate if Substrate Concentration is Higher than Michaelis Constant
Go Maximum Rate = Catalytic Rate Constant*Initial Enzyme Concentration

Dissociation Rate Constant from Michaelis Menten kinetics equation Formula

Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration)
KD = ((Vmax*S)/V0)-(S)

What is Michaelis–Menten kinetics model?

In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics. Biochemical reactions involving a single substrate are often assumed to follow Michaelis–Menten kinetics, without regard to the model's underlying assumptions. The model takes the form of an equation describing the rate of enzymatic reactions, by relating the reaction rate of formation of product to the concentration of a substrate.

How to Calculate Dissociation Rate Constant from Michaelis Menten kinetics equation?

Dissociation Rate Constant from Michaelis Menten kinetics equation calculator uses Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration) to calculate the Dissociation Rate Constant, The Dissociation rate constant from Michaelis Menten kinetics equation formula is defined as the relation with the maximum rate achieved by the system, initial rate of the system, and substrate concentration. Dissociation Rate Constant is denoted by KD symbol.

How to calculate Dissociation Rate Constant from Michaelis Menten kinetics equation using this online calculator? To use this online calculator for Dissociation Rate Constant from Michaelis Menten kinetics equation, enter Maximum Rate (Vmax), Substrate Concentration (S) & Initial Reaction Rate (V0) and hit the calculate button. Here is how the Dissociation Rate Constant from Michaelis Menten kinetics equation calculation can be explained with given input values -> 0.131833 = ((40000*1500)/450)-(1500).

FAQ

What is Dissociation Rate Constant from Michaelis Menten kinetics equation?
The Dissociation rate constant from Michaelis Menten kinetics equation formula is defined as the relation with the maximum rate achieved by the system, initial rate of the system, and substrate concentration and is represented as KD = ((Vmax*S)/V0)-(S) or Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration). The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration, The Substrate Concentration is the number of moles of substrate per liter solution & The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
How to calculate Dissociation Rate Constant from Michaelis Menten kinetics equation?
The Dissociation rate constant from Michaelis Menten kinetics equation formula is defined as the relation with the maximum rate achieved by the system, initial rate of the system, and substrate concentration is calculated using Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration). To calculate Dissociation Rate Constant from Michaelis Menten kinetics equation, you need Maximum Rate (Vmax), Substrate Concentration (S) & Initial Reaction Rate (V0). With our tool, you need to enter the respective value for Maximum Rate, Substrate Concentration & Initial Reaction Rate and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
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