Dissociation Rate Constant given Catalytic Rate Constant Solution

STEP 0: Pre-Calculation Summary
Formula Used
Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
KD = ((kcat*[E0]*S)/V0)-S
This formula uses 5 Variables
Variables Used
Dissociation Rate Constant - (Measured in Mole per Cubic Meter) - The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
Catalytic Rate Constant - (Measured in 1 Per Second) - The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.
Initial Enzyme Concentration - (Measured in Mole per Cubic Meter) - The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
STEP 1: Convert Input(s) to Base Unit
Catalytic Rate Constant: 0.65 1 Per Second --> 0.65 1 Per Second No Conversion Required
Initial Enzyme Concentration: 100 Mole per Liter --> 100000 Mole per Cubic Meter (Check conversion here)
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)
Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
KD = ((kcat*[E0]*S)/V0)-S --> ((0.65*100000*1500)/450)-1500
Evaluating ... ...
KD = 215166.666666667
STEP 3: Convert Result to Output's Unit
215166.666666667 Mole per Cubic Meter -->215.166666666667 Mole per Liter (Check conversion here)
FINAL ANSWER
215.166666666667 215.1667 Mole per Liter <-- Dissociation Rate Constant
(Calculation completed in 00.019 seconds)

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16 Rate Constants of Enzymatic Reaction Calculators

Forward Rate Constant in Enzymatic Reaction mechanism
Go Forward Rate Constant = (Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))
Reverse Rate Constant in Enzymatic Reaction Mechanism
Go Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration
Forward Rate Constant given Reverse and Catalytic Rate Constant
Go Forward Rate Constant = (Reverse Rate Constant+Catalytic Rate Constant)*(Enzyme Substrate Complex Concentration/(Catalyst Concentration*Substrate Concentration))
Reverse Rate Constant given Forward and Catalytic Rate Constants
Go Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant
Catalytic Rate Constant given Reverse and Forward Rate Constant
Go Catalytic Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Reverse Rate Constant
Catalytic Rate Constant given Dissociation Rate Constant
Go Catalytic Rate Constant = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)
Dissociation Rate Constant given Catalytic Rate Constant
Go Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
Catalytic Rate Constant at Low Substrate Concentration
Go Catalytic Rate Constant = (Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)
Dissociation Rate Constant given Concentration of Enzyme and Substrate
Go Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
Reverse Rate Constant given Michaelis Constant
Go Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant
Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration
Go Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration
Forward Rate Constant given Dissociation Rate Constant
Go Forward Rate Constant = (Reverse Rate Constant/Dissociation Rate Constant)
Reverse Rate Constant given Dissociation Rate Constant
Go Reverse Rate Constant = (Dissociation Rate Constant*Forward Rate Constant)
Dissociation Rate Constant in Enzymatic Reaction Mechanism
Go Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant
Rate of Chemical Reaction
Go Rate of chemical reaction = Change in concentration/Total time interval
Rate Constant given Maximum Rate and Initial Enzyme Concentration
Go Final Rate Constant = Maximum Rate/Initial Enzyme Concentration

Dissociation Rate Constant given Catalytic Rate Constant Formula

Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
KD = ((kcat*[E0]*S)/V0)-S

What is Michaelis–Menten kinetics model?

In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics. Biochemical reactions involving a single substrate are often assumed to follow Michaelis–Menten kinetics, without regard to the model's underlying assumptions. The model takes the form of an equation describing the rate of enzymatic reactions, by relating the reaction rate of formation of product to the concentration of a substrate.

How to Calculate Dissociation Rate Constant given Catalytic Rate Constant?

Dissociation Rate Constant given Catalytic Rate Constant calculator uses Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration to calculate the Dissociation Rate Constant, The Dissociation rate constant given catalytic rate constant formula is defined as the relation with an initial rate of the system, catalytic rate constant, and with enzyme and substrate concentration. Dissociation Rate Constant is denoted by KD symbol.

How to calculate Dissociation Rate Constant given Catalytic Rate Constant using this online calculator? To use this online calculator for Dissociation Rate Constant given Catalytic Rate Constant, enter Catalytic Rate Constant (kcat), Initial Enzyme Concentration ([E0]), Substrate Concentration (S) & Initial Reaction Rate (V0) and hit the calculate button. Here is how the Dissociation Rate Constant given Catalytic Rate Constant calculation can be explained with given input values -> 0.215167 = ((0.65*100000*1500)/450)-1500.

FAQ

What is Dissociation Rate Constant given Catalytic Rate Constant?
The Dissociation rate constant given catalytic rate constant formula is defined as the relation with an initial rate of the system, catalytic rate constant, and with enzyme and substrate concentration and is represented as KD = ((kcat*[E0]*S)/V0)-S or Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration. The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product, The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction, The Substrate Concentration is the number of moles of substrate per liter solution & The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
How to calculate Dissociation Rate Constant given Catalytic Rate Constant?
The Dissociation rate constant given catalytic rate constant formula is defined as the relation with an initial rate of the system, catalytic rate constant, and with enzyme and substrate concentration is calculated using Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration. To calculate Dissociation Rate Constant given Catalytic Rate Constant, you need Catalytic Rate Constant (kcat), Initial Enzyme Concentration ([E0]), Substrate Concentration (S) & Initial Reaction Rate (V0). With our tool, you need to enter the respective value for Catalytic Rate Constant, Initial Enzyme Concentration, Substrate Concentration & Initial Reaction Rate and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Dissociation Rate Constant?
In this formula, Dissociation Rate Constant uses Catalytic Rate Constant, Initial Enzyme Concentration, Substrate Concentration & Initial Reaction Rate. We can use 2 other way(s) to calculate the same, which is/are as follows -
  • Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant
  • Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
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